ASSOCIATION OF IMMUNE RESPONSE WITH EFFICACY AND SAFETY OUTCOMES IN ADULTS WITH PHENYLKETONURIA ADMINISTERED PEGVALIASE IN PHASE 3 CLINICAL TRIALSRESEARCH IN CONTEXT

Association of immune response with efficacy and safety outcomes in adults with phenylketonuria administered pegvaliase in phase 3 clinical trialsResearch in context

Background: This study assessed the immunogenicity of pegvaliase (recombinant Anabaena variabilis phenylalanine [Phe] ammonia lyase [PAL] conjugated with polyethylene glycol [PEG]) treatment in adults with phenylketonuria (PKU) and its impact on safety and efficacy.Methods: Immunogenicity was assessed during induction, upward titration, and mainten

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Betwixt Droughts and Floods: Flood Management Politics in Thailand

Attempting to create greater understanding head total joy 2023 of the political dynamics that influence domestic disaster relief and management (DRM) in Thailand, this article takes a closer look at these dynamics by outlining the main actors involved in flood-related DRM.It acknowledges the importance of international and military actors but empha

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Influence of molybdenum application on soil nutrient status and uptake by cauliflower (Brassica oleracea var. botrytis L.) in an Acid Alfisol soil

A field investigation was carried out to evaluate the impact of molybdenum (Mo) application on the yield and nutrient status of cauliflower gumball bere in an acid Alfisol.The experiment comprised eleven treatments, replicated thrice in a randomized block design (RBD).The highest marketable yield of 558.8 g plant-1 was recorded in treatment with a

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The Difference of the Knowledge, Stigma and Attitude between The First Year and Final Year Student of Medical Faculty of Jember University toward Mental Disorders

Mental disorders is one of the health problems in developing countries and developed countries.One of the no face no case logo biggest problems faced by those with mental disorders is the presence of that and negative attitudes due to lack of public knowledge.Several previous studies have found that education increase knowledge and change the stigm

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